Corneal Transplant Rejection More Likely In Patients With Neovascularization

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According to a study published in the July issue of Ophthalmology, corneal transplant rejection is more likely to occur in people who have abnormal vessel growth in their eyes before undergoing the surgery.

But, patients with such neovascularization might improve their chances of a successful transplant when administered antiangiogenic drugs beforehand, such as ranibizumab and bevacizumab.

After reviewing 19 studies encompassing approximately 24,500 corneal transplants, researchers also found that patients who do not have vascularization when they undergo transplantation have a greater than 80 percent chance of retaining good eye health five years after their surgery.

The U.S. National Library of Medicine has more on corneal transplantation.

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