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This retrospective study enrolled 65 eyes of 65 patients with persistent DME treated with intravitreal ranibizumab injection. The main outcome measures were the change in best corrected visual acuity (BCVA), the central subfield macular thickness (CSMT) recorded with optical coherence tomography (OCT), and its correlation with the serum hemoglobin A1c values (HbA1c).
Researchers found that serum levels of glycated hemoglobin (HbA1c) showed a negative correlation with the change in central subfield macular thickness (CSMT) after intravitreal injection of ranibizumab.
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